In order to use the data files provided on this site, you will need either ClrMamePro or RomCenter.

ClrMamePro by Roman Scherzer. The most powerful ROM manager available.	RomCenter by Eric Bole-Feysot. Easier for beginners than ClrMame Pro.

If you would like a frontend / GUI for DatUtil and MAMEDiff:

Dat Workshop Pro by Simone.

There are some alternative ROM management tools that you might also like to try...

MAME Merge by Insane. Similar to the ClrMamePro rebuilder facility.	SetCleaner by Simon Stanley Sitzia. Amongst other things it can clean MAME ROM sets.

If you are using Linux, you might find these tools useful although I have not tried them myself:

AdvanceScan by Andrea Mazzoleni.	Mamory by Pierre Mazière.